As surprising as it might seem, the answer is not always. A natural ingredient can be just as toxic and harmful as some synthetic chemicals. Cyanide, for example, is a naturally occurring substance found in many edible fruits that may result in death if ingested in large quantities.
Some of the commercially available Vitamin C, on the other hand, is synthetic, however, few would question its health benefits.
The ingredients you want to avoid, both natural and synthetic, are those that cause irritation that can trigger inflammation that increase skin sensitivity and even accelerates visible signs of aging, such as parabens, mineral oils and synthetic fragrances. This inflammatory response stresses the skin’s natural repair process, damages its protective barrier and breaks down collagen hastening the appearance of lines and wrinkles and, ironically, undermining the very function of anti-aging skin care- to slow aging of the skin.